Could playing in the dirt make you saucy ? computer mouse pass Arachis hypogaea butter laced with a vulgar , harmless soil bacterium ran through mazes doubly as fast and love doing so .

So saysDorothy Matthewsof the Sage Colleges in Troy , New York country , who presented her answer at theannual group meeting of the American Society for Microbiologyin San Diego , California , this week .

In a Greco-Roman trial of learning power , Matthews gave black eye a delicacy – bloodless bread with peanut butter – as a reinforcement to encourage them to watch to run through a maze . When she enlace the goody with a tiny moment of Mycobacterium vaccae , she found that the mice ran through the snarl doubly as fast as shiner that were given plain monkey nut butter . This intimate that they had learned to sail the maze faster , Matthews read .

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Moreover , the mice give the bacteria proceed to execute the maze faster than those without it for 18 more trials over the next six weeks , establish they were n’t just made more alarum by a surprisal change to their treat . This effect lasted for four calendar week after the last piece of doctored peanut butter was given to the mouse .

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Matthews believe this was triggered by the effect M. vaccae has on the resistant system , something that was investigate in 2007 byChris Lowry , now at the University of Colorado at Boulder .

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Lowry was trying to explain why sick people – who have set off resistant systems – often become depressed and sluggish , which could be an version that hotfoot retrieval .

His team get that exhibit mice to the bacteria , and hence activating their immune system , activated clump of neurons in their brain stem called the dorsal Raphe nuclei . These neurons connect to the forebrain and other brain bodily structure that regulate mood and behaviour .

This resultant role direct Matthews to enquire whether the bacteria ’s effect on the brain pass to a more universal difference in cognitive occasion – and she found that it did .

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Focus on that maze

The bacterium may speed up encyclopedism because the Raphe nuclei get a brain realm called the hippocampus , which handles spacial memory , she says .

But the bacterium also vary the computer mouse ’s mood – they show less behaviour that argue anxiousness , such as grooming and searching , perhaps analogous to the calmer behaviour immune activation triggers in people .

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This is likely to have been due to changes to the higher mental mapping in the prosencephalon , which perhaps take into account them to concentrate considerably on the maze .

Matthews says that photo to soil bacteria may affect human brains too . “ It just shows that we evolved with dirt as hunter - gatherers , ” she says . “ So rick off your TV and go oeuvre in your garden , or take the air in the woods . ”

Journal Reference : Neuroscience , DOI : 10.1016 / j.neuroscience.2007.01.067

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